Renal injury in DOCA-salt hypertensive C5-sufficient and C5-deficient mice
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چکیده
منابع مشابه
TNF- inhibition reduces renal injury in DOCA-salt hypertensive rats
Elmarakby AA, Quigley JE, Imig JD, Pollock JS, Pollock DM. TNFinhibition reduces renal injury in DOCA-salt hypertensive rats. Am J Physiol Regul Integr Comp Physiol 294: R76–R83, 2008. First published November 7, 2007; doi:10.1152/ajpregu.00466.2007.—Studies suggest that the inflammatory cytokine TNFplays a role in the prognosis of end-stage renal diseases. We previously showed that TNFinhibiti...
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Studies suggest that the inflammatory cytokine TNF-alpha plays a role in the prognosis of end-stage renal diseases. We previously showed that TNF-alpha inhibition slowed the progression of hypertension and renal damage in angiotensin II salt-sensitive hypertension. Thus, we hypothesize that TNF-alpha contributes to renal inflammation in a model of mineralocorticoid-induced hypertension. Four gr...
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Diminished insulin sensitivity is a characteristic feature of various pathological conditions such as hypertension and activation of peroxisome proliferator activated receptor α (PPARα) has been shown to enhance insulin resistance and reduce capacity for glucose uptake in muscles. The present study was designed to evaluate the interactions of PPARα and GLUT4 in a model of hypertensive renal inj...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1989
ISSN: 0085-2538
DOI: 10.1038/ki.1989.234